A high-yield clinical curriculum — equipping you to interpret liver enzymes, recognize chronic liver disease, manage cirrhosis complications, and navigate liver and intestinal transplant medicine.
Start Learning22 structured topics across four domains — built for every stage of medical training, from your first liver-focused history to post-transplant immunosuppression.
How to take a liver-focused history, perform the hepatology physical exam, interpret abnormal liver enzymes, and master bedside paracentesis.
Start here Core DiseaseCirrhosis and its complications, MASLD, ALD, autoimmune hepatitis, hemochromatosis, Wilson's disease, vascular liver diseases, acute liver failure, and more.
Explore topics Scoring SystemsThe MELD score (history, formula, MELD 3.0), SAAG interpretation, and the scoring systems that drive clinical decisions and transplant allocation.
Explore topics Transplant MedicineIndications for liver transplantation, the operative phases of transplant surgery, post-transplant immunosuppression, and liver anatomy for the OR.
Explore topicsEvery topic is more than a reading assignment. Choose how you engage with the material, interact with the content, and track your progress as you go.
Focus gives you a continuous-scroll layout with a sticky sidebar showing section progress. Tabbed lets you jump to any section independently. Guided steps you through one section at a time.
Work through diagnostic criteria with step-by-step checklists. Review drug classes with FlipDeck cards. Filter treatment options by category. Apply concepts through clinical case vignettes with self-quiz questions.
Mark individual sections complete as you go. Progress saves to your browser and persists between sessions — return to any topic and pick up exactly where you left off.
In 2023, 62% of transplant hepatology fellowship positions went unfilled. A projected 35% shortage of hepatology providers is expected by 2033. The problem starts in medical school.
LIMES™ was built to address the gap between what standard curricula cover and what future physicians — regardless of specialty — need to recognize and manage. Every internist, family physician, and emergency medicine doctor will see liver disease. This curriculum gives you the foundation to act on it.
LIMES™ is freely available — no login, no paywall, no institutional access required. Any medical student, at any stage of training, can use the full curriculum. Questions or feedback? We'd like to hear from you.
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